This national study sought to determine if work and COVID-19 related stressors are associated with higher levels of educator burnout and stress, if differences in levels of educator burnout and stress by sociodemographic and school characteristics exist and, how work-related Sense of Coherence affect the association between work and COVID-19 stressors on educator burnout and stress. Participants (N = 236) across primary and secondary schools predominately inside the US completed a survey that included demographic variables which were included in the analyses. Overall, work and COVID-19 stressors were positively correlated with educator burnout and perceived stress. There were statistically significant differences in emotional exhaustion and depersonalization by gender with female educators reporting higher emotional exhaustion than male educators. Also importantly, educators who considered leaving their teaching jobs reported personal accomplishment levels lower than educators who did not consider leaving and when students were a high source of stress, educator stress, reported emotional exhaustion, depersonalization, and overall perceived stress increased. Implications for policy and practice are included.