Given noted racial disparities in mental health and wellbeing, Black and Latine families are often the focus of prevention and intervention efforts. These efforts are traditionally embedded in deficit perspectives about these communities, ignoring their cultural wealth and collective agency. Yet increasing recognition of the interconnected systems and social determinants that lead to racial disparities and negative outcomes among Black and Latine populations requires counselors and other practitioners to broaden their conceptions of prevention and engage in collaboration to develop more effective and comprehensive prevention efforts. In the current paper, we provide an ecologically informed transdisciplinary model of family empowerment, prevention, and wellbeing with Black and Latine families. We apply this model to counseling practice as a potential roadmap for future counseling prevention work with Black and Latine families.